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*** NIH and Cornell IBC declare September as Safety Awareness Month .... Read more ***

Log into: e-MUA
Start/Submit/Open an Existing Memorandum of Understanding and Agreement (MUA)

Biosafety Level -3 application

Changes to the IBC electronic application system are in progress.  The IBC has initiated the migration to this new system.   In order to ensure a successful migration, some features are temporarily unavailable in the current IBC system.   Please contact the IBC Administrator if you need to amend an approved Memorandum of Understanding and Agreement (MUA) as this will temporarily be done in a paper copy format.

Contact the IBC Office

The Cornell IBC is the institutional body responsible for oversight of activities involving biohazardous materials as required by the National Institutes of Health Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines) and the Centers for Disease Control and Prevention (CDC) Biosafety in Microbiological and Biomedical Laboratories (BMBL).

All RESEACHERS must secure IBC approval for their activities with recombinant or synthetic mucleic acid molecules (r/sNA) or biohazardous materials by submitting a Memorandum of Understanding and Agreement (MUA) with the IBC. The MUA is filed through an electronic submission site (e-MUA) and covers r/sNA or biohazardous materials. Research at Biosafety Level -3 requires a separate application.

Uses of r/sNA or Biohazardous materials (list is not inclusive):

  • transgenic plants or animals
  • infectious organisms (bacteria, fungi, parasites, prions, rickettsias, viruses, yeasts, etc.) which can cause disease in humans and animals
  • human or non-human-primate materials (body fluids, tissues, cell lines, etc.)
  • biotoxins
  • select agents
  • investigational live, recombinant, synthetic or attenuated virus strains
  • plant pathogens
  • mammalian cell culture

Attention: As of March 2013, the NIH/OBA has amended the NIH Guidelines to include oversight of recombinant and synthetic nucleic acid molecules. A FAQ from the NIH detailing the changes is available; The IBC application has been modified to accommodate these changes.

How do the revised guidelines affect Cornell researchers and the IBC?

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Contact Information

395 Pine Tree Road, Suite 320
Cornell University
Ithaca, NY 14850
t. 607-255-7219
f. 607-255-0758